Research

Double Breast Cancer Survival Rates with Vitamin D

Anticancer Res. 2014 Mar;34(3):1163-6.

Meta-analysis of vitamin D sufficiency for improving survival of patients with breast cancer.
Mohr SB1, Gorham ED, Kim J, Hofflich H, Garland CF.

BACKGROUND/AIM:
To determine whether higher serum 25-hydroxyvitamin D [25(OH)D] at diagnosis is associated with longer survival of patients with breast cancer.

MATERIALS AND METHODS:
A meta-analysis was performed of five studies of the relationship between 25(OH)D and mortality from breast cancer. A pooled hazard ratio was calculated using a random-effects model.

RESULTS:
Higher serum concentrations of 25(OH)D were associated with lower case-fatality rates after diagnosis of breast cancer. Specifically, patients in the highest quintile of 25(OH)D had approximately half the death rate from breast cancer as those in the lowest.

CONCLUSION:
High serum 25(OH)D was associated with lower mortality from breast cancer. Serum 25(OH)D in all patients with breast cancer should be restored to the normal range (30-80 ng/ml), with appropriate monitoring.

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